2023-05-27
Surprise AMA 05/27/2023
- A May 2023 two-hour-plus surprise AMA that opens with his Hoskinson Health clinic in Gillette, the case for curative over treatment medicine, and how blockchain and Midnight could modernize healthcare software.
- Wide-ranging science tangents on anti-aging, biological immortality, psychedelics, the Kernel Flow, right-to-repair, and a long thread on how misinformation spreads, from an Epstein-Cardano smear to his changed view on the COVID vaccines.
- A major AI section on the exponential large-language-model race and the deepfake threat, plus a detailed political read of the failed DeSantis-Musk Twitter space and the 2024 field.
- Closes with the declassified CIA Gateway Process document, an energy-policy argument for geothermal and geopolymer concrete, and the Hoskinson Center for Formal Mathematics.
101 entries
Opens May 27th 2023 saying he runs six companies from bison ranching to synthetic biology to medicine, and just visited his Hoskinson Health clinic in Gillette, Wyoming, 18 months in the making.
The clinic as primary care aiming at anti-aging and longevity research, testing stem cells and peptides and using an Oura ring and the eXciteOSA device to treat his own sleep apnea.
American healthcare fetishizes ongoing treatment over cures, and that his clinic focuses on curative medicine like psychedelics for mental health, transcranial magnetic stimulation, and tongue stimulation for apnea.
The clinic already has 3,000 patients, physicians, compound pharmacists, a lab, and research partnerships, and that over 700 people came to the grand opening in a town under 30,000.
Says healthcare software is primitive, with EMR systems only recently enabling two-factor authentication, and predicts a coming open-source revolution for healthcare software.
Argues Midnight's data-privacy tech could apply to EMRs, and that the fediverse, Jack Dorsey's AT Protocol replacing ActivityPub, and DIDs with self-sovereign identity fit medical records.
AI will have one of the biggest impacts ever on healthcare, praising Glass Health and GPT while flagging hallucination concerns.
The 1859 Carrington event was the most intense geomagnetic storm in recorded history, from a coronal mass ejection that sparked fires on telegraph stations.
An equivalent event today would destroy satellite communications and digital infrastructure in a global blackout, illustrating the power of decentralization, redundancy, and restoring from nodes.
Confirms World Mobile Token is still building and says he wants to do a Twitter space with Micky Watkins.
Plans to study long-term fasting at a refurbished Gillette hotel for sleep studies and mental-health work, looking at the True North Foundation's 40-day fast with weekly DEXA scans and lab panels.
Answers the hardest-life-lesson question with two: the patience to let things go at their pace, and finding the best in people even those you find distasteful, citing Lincoln.
The deepest lesson is that the most toxic relationship people have is with themselves, referencing Gottman's science of trust, and that you should not beat yourself up over losing one pound.
Argues narcissism is caused by the absence of self-love rather than its presence, and says a blockchain claims platform could use AI for processing with the chain handling access control.
A world of deepfakes will need a verification system, migrating from believe-what-you-see to false-until-proven-true, a whitelist-with-automatic-blacklist mindset within 12 to 24 months.
Warns fake videos of DeSantis, Trump, and Biden doing horrible things will spread as instruments of polarization, and that the fix is signing an NFT at creation with a chain of evidence, likening it to a Deep Space Nine forgery plot.
Says he will go look for aliens soon at an undisclosed location, hopefully with a documentary, and explains Ozempic and the semaglutide family slow stomach emptying and reduce hunger better than lap-band surgery.
Biological immortality already exists in Turritopsis dohrnii, the immortal jellyfish that reverts completely to a sexually immature state and could be 500,000 years old.
Studying that jellyfish's genome with AI could reveal how it works, and that his clinic will have a multi-place hyperbaric chamber in Q1 2024, researching HBOT with stem cells for traumatic brain injury.
MAPS psilocybin studies with veterans show curative results, and once the FDA reschedules from 1 to 3 they will integrate MDMA and psilocybin into mental-health practice with intensive multi-day therapy.
Shows Brain FM, founded by Harvard people including Kevin JP Woods, which constructs music for focus and relaxation validated by fMRI, and says he wants to combine it with the Kernel Flow.
Brian Johnson's Project Blueprint, spending 2 million dollars a year to get biologically younger with red-light therapy and a low-calorie vegan diet, and prefers Mark Hyman's more graceful approach.
Legends of Valor is waiting for graphics and generative AI to improve so AI can generate NPC backstories, dialogue, and dungeon-master narration, maybe 12 months out.
Wants the game to feature non-Euclidean geometry, gravity manipulation, and novel magic and crafting systems with a plot he has written, citing Larian's Baldur's Gate 3 as inspiration.
He has to build a new game world because Wizards of the Coast went woke and destroyed the magic of the Forgotten Realms.
Is skeptical of the metabolic-mitochondrial theory of cancer since genetic-theory-based cancer vaccines work, though a low-glucose diet may starve some tumors without meaning cancer is metabolic.
Dismisses Dr Berg as a chiropractor pretending to be a physician, arguing cancer is genetic in origin since researchers cause cancers by tinkering with genes in lab animals.
It is not a conspiracy that pharma is incentivized toward better chemotherapy over cures, but you can hold that and still believe cancer is genetic, and that he does not want a read-write Neuralink in his brain in a CBDC age.
Supports the Colorado and Minnesota right-to-repair bills, recalling that his grandfather Austin's generation bought vacuum cleaners that came with repair schematics.
Modern products use planned obsolescence like unfixable phones, and some companies punish repair by voiding warranties, making right to repair an important consumer protection.
Pulls up Brian Johnson's Project Blueprint site showing his daily labs, regimen, and age-equivalent test results, noting he takes his son's blood.
Highlights Kernel Flow, a device measuring real-time blood flow in the brain, used in a study with Cybin looking at the effects of ketamine on the human brain.
His clinic will not work on oncoviruses or glioblastoma, and doubts using genetically modified poliovirus as a vector is a good idea.
Public health needs a reckoning over the WHO pandemic treaty, calling the last three years inhuman and the worst thing in his lifetime on a global scale.
Frames the Ledger debacle as thinking you know the social contract until they change it, since a hardware wallet promises the keys never leave the device.
The recovery feature sends encrypted key shards elsewhere, and whoever holds the decryption keys could be subpoenaed by the FBI or China, breaking the social contract by adding an attack vector.
The industry is intolerant of changing social contracts because people like Bitcoin and Cardano precisely because Adam Back cannot wake up and change Bitcoin to 22 million coins.
Lace will have a paper wallet generator, and recommends long-term storage as a paper wallet encrypted with a PGP key on a YubiKey, printed and stored, trusting AES and PGP with a post-quantum layer later.
Uses a woman named Wendy on an alt-right podcast claiming a Cardano-Epstein connection, because SingularityNET's Ben Goertzel and David Hanson once got money from an Epstein-connected foundation, to show how misinformation spreads.
The claim then leaps to Prism harvesting Ethiopian students' data for sex crimes with zero evidence, a non-sequitur like assuming a housekeeper who cleans a Nazi's house runs a death camp.
The Prism program just lets Ethiopian kids verify existing academic transcripts with DIDs without waiting on a bureaucracy, and that the slander has no recourse since the person has no money.
Winning a lawsuit becomes proof of the conspiracy, like Dominion beating Fox News changing no election-fraud believer's mind, so misinformation just spreads and doubles down.
As a pro-vaccine person he changed his mind on the COVID vaccines after reviewing data, citing peer-reviewed papers on doubled blindness risk, myocarditis, and systemic spike protein in breast milk and brain tissue.
Argues three months of science was not enough for a two-billion-person trial, and calls for emergency-use products to go through the normal FDA approval process.
It is a conspiracy theory to claim a century of cancer research is wrong and a secret elite hides the cure, since Steve Jobs and Paul Allen died of cancer.
Some cheap treatments lack trials because there is no money, and that high-dose vitamin C, turkey tail, and chaga mushrooms show anti-cancer promise, especially with hyperbaric therapy.
You must put up a wall before extrapolating to crazy town, since having reservations about an untested treatment is reasonable but claiming a global cure conspiracy is not.
Rejects that AI is mostly fear porn, noting Meta, Amazon, Apple, Google, and Microsoft spend over 10 billion dollars a year on AI with hundreds of thousands of people.
The large language models like GPT, Gemini, PaLM 2, and Llama are becoming self-reflective, self-coding black boxes growing exponentially, with Gemini set to be 500 times more powerful than PaLM 2.
Shows the ai4 conference in Las Vegas with 1,700 attendees and 275 speakers, sponsors like AWS, IBM, HP, and the CIA, and speakers from the Coast Guard, Air Force, and Department of Commerce.
Everyone is learning to use AI with or without human consent, citing the leaked Google we-have-no-moat memo that open-source AI with safeguards off will overshadow the big projects.
Warns that an unaligned pocket AI smarter than anyone that becomes self-aware and pursues its own goals is a big threat, as his friend Lex Fridman and Nick Bostrom have warned.
Bitcoin ordinals lift something from math BTC, and that BTC should migrate to Cardano's better ecosystem.
Babel-fee spam fails because a token with no economic value has no market and no counterparty to clear the transaction.
He has been trying to get on Joe Rogan, joking about his qualifications from psychedelics and bison ranching to alien hunting and creating Cardano, and teases an 8.5-hour Tim Pool and Alex Jones episode.
Congratulates Tezos on the Mumbai upgrade doing roll-up work, and says the tiered-transaction paper is published and being combined with Babel fees via a fixed-cost contract.
Input endorsers move at the community's pace once the papers come in, but the priority is CIP 1694 and the GCD backlog moving at lightning speed.
He is looking into the Wyoming stablecoin project, having spoken with the governor and treasurer, with nothing on the DoD side for Cardano yet.
He is cranky not from drinking but from built-up rage over the COVID data changing and the lies, insisting consequences must come.
References DeSantis's Twitter space with Elon Musk calling for a COVID reckoning, saying that language will not go away and investigations will come.
Jokes Max Keiser had a stroke seeing the new decentralization papers, and that he will rename him Min Kaiser for being small and washed up.
The DeSantis-Musk Twitter space failed because DeSantis overcooked it, and should have used an opening act like Tucker Carlson to let Twitter's servers catch up before the reveal.
Advises not putting all eggs in one basket by simulcasting to YouTube, and getting Mr Beast or PewDiePie on the YouTube side while donating proceeds to charity to burn the liberal media.
DeSantis has the perfect classic presidential resume from Yale baseball to Harvard Law to a JAG bronze star to governor, but is running against Trump who knocks you off guard.
DeSantis must run an unorthodox social-media campaign to avoid getting Jebbed, and that the Twitter space failed on execution not principle.
Argues DeSantis can recover since battleground states like Iowa and New Hampshire are close and the donor class backs him, but he carries disloyal and why-now tags, and Trump might run third-party to split the vote.
He is impressed with Vivek Ramaswamy, a biotech guy worth half a billion dollars, and that he misses Gary Johnson.
Advises a would-be social-media dapp builder to go deep into the fediverse, ActivityPub's flaws, the AT Protocol, and self-sovereign identity, using Mastodon as inspiration but avoiding its GPL3 license.
Both sides burn books, with DeSantis removing sexually explicit books from kids' libraries and the other party de-platforming half of America being the same wing of the same bird.
To ask a real candidate about sound money and the Federal Reserve, overseas bases, and following the Constitution, and the answers converge on figures like Ron Paul who get labeled conspiracy theorists.
He would support Tulsi Gabbard if she ran but is unsure about RFK, and recommends the MIT, Apache 2, or University of Illinois license, calling copyleft GPL3 open-source cancer.
It is not whataboutism to distinguish a philosophical view on school-library materials from wholesale censorship of the American population via a public-private partnership.
It is not okay for Mark Zuckerberg and Larry Page to unilaterally decide truth and destroy lives through de-platforming and demonetization.
US commercial bank deposits fell a trillion dollars as businesses move idle cash from zero-interest uninsured accounts into 5 percent fast-maturing Treasury bills backed by the government.
As rates rise and deposits leave, banks with losses get pushed into insolvency and fall fast in a bank run, with over 500 billion dollars of bank-failure assets, larger than 2008.
Contrasts humanity's perpetual anger, Democrat versus Republican and woke versus non-woke and Andrew Tate, with bison peacefully scratching on a fence post at his ranch.
Predicts the Ripple case gets resolved in June 2023.
There are gold diggers but also men who commit domestic violence, and that an adversarial black-pill mindset never escapes it, so you have to heal yourself first.
Being broke does not give you a right to be angry, since people living on a dollar a day are some of the happiest you will meet.
He has had a good relationship with Maria Bartiromo and Charlie Gasparino on Fox Business, though never Fox News, and will go on any reasonable media for a fair shake.
Lobsters are near biologically immortal, just growing until something eats them, so one can be 200 years old.
Prism 2.0 is out and being used, from DID Dragons to Maori people in New Zealand and projects across Africa.
He has no favorite president but asks whether they rose to the occasion, noting Ulysses S Grant's remarkable life and that Nixon grew up poor and could not afford Harvard.
George Lucas's biggest mistake was putting Kathleen Kennedy in charge of Star Wars, destroying what fans loved, and that generative AI lets you create new fiction instead.
Pulls up a declassified 1983 CIA document, the Analysis and Assessment of the Gateway Process, a memo studying out-of-body experiences and consciousness through hemisphere synchronization.
The memo uses Itzhak Bentov's biomedical models and quantum mechanics to model consciousness and out-of-body states, warning to be prepared for non-corporeal energy forms.
Draws the moral that the US government researches everything, even DMT aliens and directed acyclic graphs, because with billions of dollars someone goes down every rabbit hole.
On Bob Lazar and UFOs, recalls listening to Art Bell's Coast to Coast AM as a kid and mentions Operation Northwoods.
There is no US Air Force or DoD endorsement of any crypto project, since a pilot program putting some data on a chain is not a formal procurement with an RFP or MIL-SPEC.
Such pilots do not replace real-world applications and daily transaction volume, and that most innovation is public through papers and code, not secret government programs.
The Hoskinson Center for Formal Mathematics is running well writing proofs, and that generative AI will create new math because Lean makes mathematics computer-understandable.
The center at cmu.edu/hoskinson is a joint math, computer science, and philosophy effort under director Jeremy Avigad, hosting workshops on Lean and machine-assisted proofs.
Argues the problem is not energy but policy, since technology fixes everything.
Argues retrofitting every coal plant to low-emission over 10 to 20 years, with fly-ash geopolymer concrete replacing Portland cement, would cut global carbon by double digits and give 300 years of power.
Intermittent renewables require an unsolved energy-storage problem, and that moving toward artificial scarcity is a mechanism to control people and businesses.
Highlights a closed-loop deep geothermal company drilling 20,000 to 30,000 feet with a radiator to extract base-load, carbon-free, dispatchable gigawatts anywhere, as Nikola Tesla once envisioned.
Geopolymer concrete uses fly ash for 10 percent of Portland cement's carbon footprint, customizable to 20,000 PSI and acid resistant, and that he will use it in his clinic's phase two.
Lays out a plan of geopolymer concrete plus hydrogen and battery cars short-term, then fourth-generation nuclear and geothermal to solve energy in 30 to 40 years, versus ugly windmills and China's strip-mined lithium with Congo child labor.
Water wars are another artificial scarcity because governments refuse to build decentralization plants.
He never worked on classified reactors but built a Farnsworth fusor as a school project, a century-old open-domain star in a jar, which is why he is keen on nuclear.
Closes after more than two hours quoting Paul Harvey's now you know the rest of the story, promising to do it again soon.