2023-02-25
Surprise AMA 02/25/2023
- A late-February 2023 surprise AMA opening with the roadmap wrapping a seven-year agenda, the CNN and CoinDesk acquisition rumors, and an AI workflow that auto-summarizes his videos.
- A long Plutus whiteboard on extended UTXO, Marlowe, the surface-language-plus-core model like the JVM, and the abandoned K-framework and Yella approach, plus a generative-AI demo.
- An extended look at the Hoskinson Health clinic in Gillette, from transcranial magnetic stimulation to a mole scanner, and a sweeping critique of COVID vaccine and mask policy.
- Wide tangents on Davos hypocrisy, the Harry and Meghan South Park episode, Andrew Tate versus stoicism, and closing that everyone just wants to be listened to and loved.
84 entries
Opens February 25th 2023 after a week of executive workshops with a CIP 1694 workshop in early March 2023, noting he got COVID in January with two weeks of brain fog.
Cardano is on the rebound with four things, UTXO-HD, peer-to-peer, Genesis, and 1694, wrapping a seven-year agenda, then input endorsers, side chains, Mithril, and recursive snarks, while Hydra meetings grow with MLabs, SundaeSwap, the CF, and Obsidian.
The contingent-staking debate drew over 2,000 to a Twitter space, and that such engagement is a healthy sign rather than a bear market.
Denies a rumor tweeted by Ross Calvin that he is buying CNN, saying he made no offer and knows nothing of traditional broadcast media.
Confirms he signed an NDA to look into CoinDesk but cannot say more and doubts he will acquire it, noting acquisitions are dynamic with disagreements over value.
Shows The Business Case for AI by Kavita Ganesan, a good intro for business professionals on separating AI fact from fiction.
An automated pipeline using Otter AI and ChatGPT to transcribe and summarize his videos into 300-word summaries with keywords routed to the relevant teams, with no humans involved.
On Ada Whale leaving Twitter over contingent staking, says there is no CIP, no urgency, just a conversation, and you do not take your bags home when a debate moves against you.
Confirms multi-staking from one wallet is coming, slated for the PI cycle after April.
He bought the NES game Crystal Mines and plans a free one-click browser JavaScript version with Willie.
Recommends Barbara Oakley's free Coursera course Learning How to Learn, and notes he practices regenerative agriculture restoring his ranch's hay fields.
Colossal closed a 130-to-150-million-dollar round at a post-billion valuation, now a unicorn still on track to bring back the mammoth, and that Lace is at the last mile stuck on CIP-30 integration.
For layer 2 and zero-knowledge they are looking at pasta curves and BLS, and that they acquired Dr. Vanishree Rao from Mina.
He knew Coinbase was building a layer 2 because they tried to poach IO people and spilled the beans in the attempt.
Praises Ripple CTO David Schwartz as a real person unafraid to share opinions, now in the doghouse with the XRP community.
You will see the Ouroboros Leios paper in 2023 but not the CIPs or final design, since it changes reward mechanisms and security assumptions and requires 1694 to ratify.
Bill Gates should stay out of the food system, expressing discomfort with him buying land and animals and pushing insects.
Tells a reader of the Understanding Cardano book by John Green to keep chapter notes and email John to improve it, and says ordinals are a mathematical object about cardinality and infinite sets.
Opens a whiteboard on the claim that Plutus is too difficult, recalling the Cardano SL and CL design from 2017.
He invented extended UTXO for a fast settlement system, the native asset standard inspired by color coins, and researched two languages, Plutus and Marlowe.
Marlowe was the asset-transfer language and Plutus the connecting tissue to build bridges to more expressive layer-2 and side-chain systems.
By 2023 Plutus became general-purpose enough to closely match the EVM and Solidity, but the exciting innovation is in layer 2 like Coinbase and Polygon, as DCSpark's Seba noted.
The strategy where Plutus has a Haskell-like surface language compiling to Plutus Core, System F-omega, and you optimize the core while promoting many surface languages like Aiken and Marlowe.
Cites Java as precedent, where the JVM is the backend and Scala, Kotlin, Clojure, and Julia compile to it with big developer-friendly ecosystems, a possibly superior model.
Recalls the K framework idea where formal semantics enable semantics-based compilation to auto-generate tooling, done at the University of Illinois by Grigore Rosu creating Yella, his favorite approach that never worked for Cardano this generation.
Marlowe hits mainnet in March 2023, Plutus V2 has much better tooling, surface-Plutus-plus-core becomes the formal-methods path, and high-accessibility languages need grants from the MBO, Catalyst, and the Foundation, which funds Aiken.
Accidentally leaks from the Cardano 360 PI planning that mainnet contracts can now run on mainnet.
Demos generative AI by having ChatGPT write a song about a cat in the style of Nine Inch Nails, explaining it generates pictures, music, video, and text.
Predicts in three to five years pipelines will chain text-to-music-to-voice-to-video generators, so you could make a William Shatner-voiced parody hit and upload it in two minutes, changing everything.
Generative AI has profound IP considerations, so you should connect NFTs to it where each generation makes a companion NFT with timestamp, IP, and authorship.
NIPoPoWs are done and implemented, with no reason for them on proof-of-stake Cardano but every proof-of-work chain should use them, and that they are exploring combining Conclave with Djed so small stake pool operators can plug into a federation.
Cites the AI companion company Replika turning off its intimacy module and traumatizing users into depression, showing people bond with anything, and predicts hundreds of millions will have AI companions as they approach the Turing test.
An AI companion's parameters could be an NFT you own so a company cannot suddenly kill your girlfriend.
Confirms an Africa investment and a setup in Kenya, and that the Ethiopia deal has legs targeting a million students by the end of 2023 and 5 million in 2024, possibly becoming a national ID system.
The last WEF at Davos sickened him, a party of John Kerry, Hillary Clinton, and Marissa Mayer telling you to eat grasshoppers while private jets land every 15 minutes to talk about global warming.
Calls Davos horrifically expensive with 10,000-dollar-a-day hotels and a color-coded badge class system, supporting Jordan Peterson creating alternatives.
Proposes a free online metaverse conference open to the whole world, since a conference deciding the world's direction should be as open as possible.
Rebuts the hiding-fortune-in-businesses framing, saying he builds companies like Nessie's Scottish restaurant, a game studio, and the Gillette clinic that create jobs with health insurance, 401ks, and higher wages.
Wealth is a moral obligation to build for your community, and that he consulted the Buck Institute, David Sinclair, Dave Asprey, and Peter Attia for an anti-aging clinic.
Experts told him to build the clinic in Boulder or Denver, but he chose Gillette Wyoming, the suicide capital and a healthcare desert where even the wealthy get bad care with one doctor for every three needed.
Building the clinic from the 4,000-square-foot Skyline Grill restaurant expanded to 10,000 square feet with terrazzo floors, coffered ceilings, soundproofed exam rooms, and careful patient flow.
Digging the sewer took 18 months down 28 feet under OSHA trench rules across four properties, and that they installed 19 geothermal wells, a first for Campbell County.
The temporary clinic already has 2,000 patients and hundreds of weekly calls, before the CLIA lab, compounding pharmacy, and imaging center with the area's first 3-Tesla MRI, 256-slice CT, PET, DEXA, and SPECT.
The clinic is the first in Wyoming to buy a MagStim transcranial magnetic stimulation device, FDA-cleared and Medicare-approved after two failed SSRI lines.
TMS cures depression a third of the time, improves it a third, and does nothing a third, better than drugs and often permanent, needing 36 treatments over 90 days with over 100 placebo-controlled trials.
He also bought an AI whole-body mole scanner that flags cancerous moles in 10 seconds, state-of-the-art equipment like Mayo or Johns Hopkins brought to Gillette because he made money.
Attacks the socialist mentality that people of means are the enemy, arguing the US government does not show up when a train derails but sends money overseas, so people must take care of their own communities.
Lists his projects, a Wheatland restaurant, a profitable ranching model so ranches do not sell to Bill Gates, and curative medicine, noting CoinTelegraph's top-100 list ranked the Vasil hard fork 26th and left him off.
You do it because it is the right thing not for fame, and that Nessie's will have the largest whiskey bar in Wyoming.
He wants to do a show with Tamara Hassan called Chess and Ginger Snaps.
The clinic is hiring a licensed psychiatrist, exploring ketamine therapy, MDMA rescheduling, TMS, and photobiomodulation for TBIs alongside CBT and ACT.
He delivered on the promise of the best proof of stake ever, since Ouroboros has the best security, organic decentralization, the Genesis asynchronous model, a large validator set, and liquid non-custodial staking.
Peter Attia and David Sinclair do not really differ, since the rate limiter is translating epigenetic-aging science to human clinical trials requiring FDA approval.
Verticalizing a primary-care clinic into clinical trials with imaging and genomic sequencing lets an MRI cost 40 dollars instead of 1,200 and a CBC cost 25 cents for research.
With full-genome data and AI you can find genetic reasons some patients respond better to resveratrol or NAD, and bring fringe-but-proven therapies like photobiomodulation, TMS, and hyperbarics into medicine.
He does not understand why hyperbarics was not used for COVID patients struggling to raise their pulse ox, or ozone therapy which was used on Ebola.
Cites a paper on ozone and oxidation therapy for infectious disease, saying it is ignored because it is cheap and unpatentable.
He took both Pfizer shots plus a booster and got COVID four times, was told he would not get it and it would be mild, none of which was true, but that you cannot say that as a doctor without being de-platformed.
The big psychedelic-depression research is Roland Griffiths's psilocybin trials at Johns Hopkins, and that LSD was discovered by a Swiss chemist who took a heroic dose and rode his bike home.
He wanted the Novavax vaccine, based on the Hepatitis B nanoparticle design with no RNA or DNA, but the FDA kept it off the market for years forcing RNA vaccines.
Cites papers showing the RNA meant to stay localized travels through the whole body into breast milk and liver a month post-vaccination, arguing a manufacturer should research when its product does what it said it could not.
Vaccines normally take 15 years, with the Ebola vaccine started mid-90s and released in 2009, so declaring the science settled after one trial and de-platforming dissent is not how medicine works, like the 1970s swine flu bungle.
MRNA had nothing to do with respiratory viruses, since Moderna and BioNTech built it as cancer immunotherapy vaccines founded by oncologist MD-PhDs, applied to a respiratory virus, while Novavax was more orthodox.
Half of America may never trust public health again, and that mask meta-analyses of over 600,000 people show masks do little, while good PPE requires never taking it off unlike restaurant mask policy.
With Omicron's high R0 there was no difference between a cloth mask and unmasked below N95, that it is about exposure time, and that Canada recommending sex with a mask on destroyed trust.
He only trusts science done outside the US, like the RNA-in-blood study from Denmark, because the NIH's toxicity taints it, and that while most people in the system want to help, the system is here to control and make money.
The FDA was created to protect against charlatans like radium water and cocaine morning-sickness cures, but that ecosystem is now weaponized so any dissent costs your medical license.
Shows the eXciteOSA device, put in your mouth 15 minutes to electrically stimulate the tongue so its muscle stays stiffer, treating sleep apnea and snoring in 90 to 120 days.
The device brought to Miami was a stake pool Marcus Guffler created, and that the eXciteOSA needs a US prescription but is curative unlike a CPAP mask worn forever.
Any racial supremacy including white supremacy is wrong, all people are equal, and nobody is superior by the color of their skin.
On the South Park royal-family episode, says he does not care about the royal family since the US fought a war so it would not have to, but that Harry was born into the upper 0.0001 percent and earned nothing.
Harry claims mistreatment by a 2,000-year-old institution while writing a book, doing interviews, and a Netflix documentary asking for privacy, and offers to hide them on a Wyoming ranch where he has never even run into Jeffree Star.
Argues people who go through real horrors like domestic violence grow up poor worrying about rent and power bills, so it is not clear why Harry's privileged lived experience is worse.
South Park exposes the hypocrisy between what the famous say and do, that threatening to sue only damages the reputation, and that he is sensitive to it because journalists turned early-Ethereum drama with a 19-year-old Vitalik into books and movies claiming that is reality.
He will return to Zanzibar when World Mobile's aerostat blimps cover the whole island, now at 25,000 people heading toward 2 million.
He is living Yellowstone, having bought a ranch incinerator named Integrity that sequesters carbon for bison and horses that die, since burying a 3,000-pound animal in frozen ground is impractical.
Criticizes Andrew Tate as a poser broadcasting false machismo, saying real men are the quiet professionals like his Green Beret security who never talk about it.
Tate and Dan Bilzerian build an industry taking vulnerable people and selling a fantasy lifestyle with no character or integrity behind it.
The strongest people are indestructible, rebuilding after death camps through stoicism from Seneca and Marcus Aurelius and Viktor Frankl's logotherapy developed after the concentration camp.
Says you are on the right track when the media calls stoicism a dead slave philosophy, since stoic people do not need the garbage philosophy crammed on society, and admits he would still have friends if he had been stoic about the XRP flap.
Men and women are interdependent partners, so both fourth-wave feminism and traditionalist women-in-the-kitchen are wrong, and that John Gottman's a-tune concept of bids builds good communication.
Once you communicate well and live with integrity you set boundaries and keep people who respect them, ranging from a weekly bar acquaintance to a near-death Paraguay adventure.
Praises Lex Fridman as the realest guy he has met, intellectually curious with his heart on his sleeve, an AI PhD who taught at MIT and a jiu-jitsu black belt you would never know it.
Closes that stripped of wealth and credentials the most fundamental thing everyone wants is to be listened to, loved, and cared about, like the happy smallholder coffee farmer he met outside Addis Ababa living on a few dollars a day.