Surprise AMA 11/26/2023

Opens November 26th 2023 recovered from illness in his ninja suit, launching a surprise AMA before some cold-plunge work.

Recaps a whirlwind month through Dubai, Abu Dhabi, and Greece, turning 36, and calls the Cardano Summit amazing as projects reach the next stage.

Recalls the 2021 Laramie summit and marvels at builders now shipping in a deep bear market, naming Optim, Indigo, Djed, and dozens of NFT projects.

Rebuts FUD that Midnight distracts from Cardano, since a service layer of many chains is the whole point, while Ouroboros Peras, Genesis, and Leios input endorsers, Plutus V3, and SanchoNet at 86 percent all progress.

Calls 2024 the year of governance after building it in 2023, warning it will be hard, and is excited about BLS support and CIP 1694.

Africa continues with John O'Connor in Kenya rolling the pilots into a RealFi company serving millions, and Ethiopia going on despite a war and not being paid.

Recalls how in 2021 the NFL, Formula 1, Formula E, Susie Wolff, and the Milken Institute all courted crypto, then after FTX and Luna collapsed the government turned on it, though the philosophy never changed.

There is no formal Polkadot relationship, but Parity Substrate components like the pallet system inspired Midnight and the partner-chain toolkit, heavily modified in Rust.

Two projects, the partner-chain toolkit as a blockchain builder kit and Midnight downstream of it, both in Rust, with the Midnight devnet already signing up over 1,500 teams.

He has not earned a Blackhawk pilot license yet but plans to within 24 months, and that Logan the lobster is always on the mic.

On Vitalik talking about UTXO more, says he is rediscovering what Cardano learned from Satoshi via peer review, which teaches you before deploying to millions.

Names Russian River Valley his favorite American wine, and quips the better question is whether Solana is competitive against Cardano.

Addresses a disgruntled troll citing ex-employees who violate their NDAs, noting every entrepreneur from Steve Jobs to Elon Musk leaves a wide wake and makes enemies.

Even a rock star has an 80 percent approval, and the angry 5 to 10 percent leak and attack, so building requires the courage to be disliked and a thick skin.

Points to the broad brushstrokes: nearly 200 papers, a 12-billion-dollar ecosystem, 4 million users, and a top-10 spot, arguing critics mean you have achieved something.

He gets judged at his worst moment, like misreading the Binance ruling as 1.6 trillion dollars in fees, or the do-you-know-who-I-am tweet, replayed forever.

Says if you are very successful half the country hates you for no reason, and notes Jordan Peterson's point that there is no correlation between academic success and creativity.

Growing your own stem cells absurdly makes them a new drug needing 10 to 15 years of FDA trials, and that trying to fix such things makes half of America hate you.

On Argentina's new president Javier Milei, an Austrian-school libertarian who wants to abolish the central bank, says he would love to meet him and get him onto blockchain services and voting.

Having an opinion divides your audience but that is fine, and if you only listen to people who agree, you live in a very small world.

On the SEC, says everything is a security under the overly broad 1933 Howey test litigated through enforcement, causing catastrophic harm to the industry.

The US regulates by boxes, FinCEN and the BSA for currency, the CFTC for commodities, the SEC for securities, but a crypto asset can be all at once with no registration path.

Recounts Coinbase filing an S1 in 2021 that the SEC approved for an IPO listing ADA and others, then two years later suing it as an unregistered broker-dealer for the identical model.

The executive branch knows lawsuits take years, so this is a failure of Congress to pass clear rules, and that a protocol run by thousands of independent people is a commodity, not a security.

Argues that like gold, a commodity's value survives killing any CEO because it is a permissionless marketplace, unlike Microsoft's licenses.

Demands the SEC run the Howey test and explain the difference between Bitcoin, Ethereum, and Cardano, noting three subpoenaed entities could 51 percent attack Bitcoin yet team orange gets a pass.

Praises libertarians as the only ones unraveling an unaccountable government, and says crypto exists to reestablish a horrifically broken social contract.

The US is 31 trillion dollars in debt and the American empire cannot sustain itself, while 80 to 90 percent of Americans are unhappy with all three branches yet nothing changes.

The American people are hardworking, like Gillette Wyoming in minus-five and 100 mph winds, and import smart talent globally, but the government is a catastrophe with no accountability.

The media was the fourth estate with the Pentagon Papers but now vilifies Julian Assange and WikiLeaks, so crypto is a two-pronged fix.

Gen Z owns this movement and the federal government is unchangeable, since Obama with a supermajority did not go after Wall Street the way Iceland did, and Trump could not either.

The Deep State cannot be voted out, so the only escape is a constitutional convention of two-thirds of states that the founders provided, which Cardano is learning how to do.

Wants a leader born in the second half of the 20th century, and says the central banks need to go.

Recalls The Simpsons of 1988, where a high-school dropout single earner supported a family, two cars, and a house, now impossible for two college grads because inflation robbed everyone to pay for wars.

On NAD and IV therapy, situates it among anti-aging supplements like metformin and rapamycin for mitochondrial health and recommends three definitive books.

Names the three anti-aging books: David Sinclair's Lifespan and his information theory of aging, Peter Attia's Outlive, and Tony Robbins and Peter Diamandis's Life Force.

Before any anti-aging drug you must do four things well, eat right, exercise, sleep well, and fix your emotional health, or your health span is compromised.

Only after those four foundations do supplements, hyperbarics, NAD, rapamycin, stem cells, and exosomes matter, noting night-shift workers die 15 to 16 years earlier.

Would love a fireside chat with Wyoming neighbor Caitlin Long, and notes the Pentagon audit failed for six years with 3 trillion unaccounted.

Kraken is a fellow Wyoming business they get along with, lamenting the constant toxicity from others.

Gives an EDI update: eight metrics with the network stack measured, and a team going to Abu Dhabi's ADGM and Dubai's VARA to make the Edinburgh Decentralization Index the definitive regulatory metric.

Wants EDI shown on CoinMarketCap, CoinGecko, and Messari beside price, with a team led by Daniel Wood working on the eight dimensions of decentralization.

Hoskinson Health has 5,000 patients and a half-dozen providers, with phase two construction set to triple the clinic and enable anti-aging human trials in Campbell County.

JJ was promoted to Chief of Staff, and that the recovered-microspherule paper will publish in spring 2024.

Follows Rhonda Patrick's sauna research and uses a Red sauna up to 170, and complains that Huberman was labeled misinformation while his own videos and AMAs were taken down.

Argues these systems must be decentralized rather than relying on Elon spending 40 billion on Twitter, and that Colossal is on schedule resurrecting the woolly mammoth.

World Mobile is doing well and he loves Micky, having just seen him at the summit.

Defends the woolly mammoth as a symbol for restoring biodiversity, since dozens of mammals go extinct every day and the alternative is halving the biodiversity of future generations.

Gives relationship advice to a single 35-year-old: work on yourself, lower your debt, get healthy, and become a well-adjusted beacon so people gravitate to you.

The Davos story with Nathan Kaiser: badge classism ranked everyone by money while people virtue-signaled about DEI, ESG, and SDGs after flying private jets.

Warns the powerful virtue-signalers at Davos come to believe they should run your life through the Fourth Industrial Revolution, an eat-bugs-own-nothing dystopia.

The antidote is decentralizing power to give people control of identity, voting, consent, and money, and that anyone who violates those three is the enemy.

He is done with the WEF globalist mindset after two-weeks-to-slow-the-spread became papers-please and forced vaccination, now cemented in transnational treaties.

Jokes he already eats bugs and likes scorpions, and says the ETHDenver venue is too packed and should cap attendance.

Argues military, airline, healthcare, and education employees were forced to vaccinate or lose their jobs, which is coercion not consent, comparing it to sexual coercion.

Invokes informed consent as the basis of medical ethics, violated when journals suppress anything negative about vaccines to avoid promoting hesitancy.

New York courts ruled mandates unconstitutional and workers got their jobs back, and that a not-yet-FDA-approved vaccine got one trial before being given to billions.

Admits he took the Pfizer vaccine himself in 2021 and trusted them, and says his sister lost her nursing job despite natural immunity, which authorities falsely called weaker.

The Nessie restaurant backstory: buying the Hilltop in Wheatland Wyoming for a Scottish restaurant with bison and a plesiosaur skeleton, snarled by a hidden lawsuit and a botched deed.

The Hilltop parking could not expand, so it is becoming a members-based Hoskinson Club with whiskeys, a cigar room, and games, while Nessie moves to another site.

The CEO Jan came from an exhaustive search, having been Polkadot's chief operating officer and having run Symphony.

Debunks the collective-vaccination argument, saying without a global plan like smallpox or polio, billions act as a reservoir and the virus mutated past the vaccines.

His mushroom farm burned down, and that vaccine efficacy against variants is under 15 to 20 percent.

Praises the Walter Reed universal COVID vaccine and Novavax's protein-subunit vaccine, from Chilean tree bark with a hepatitis-B lineage, both stuck in the FDA process.

Synthetic biology's existential risk, combining a high-R-value virus like Omicron with a lethal one like rabies via gain-of-function in thousands of unregulated labs.

His CRISPR-Cas9 plant work and de-extinction gave him domain expertise, that the same techniques design viruses, and the COVID lesson should be treating synthetic biology like the Atomic Energy Commission.

Mithril could link a node on a colonized planet to Earth via Ouroboros Genesis, and that Midnight was built to custody medical data for future medical LLMs.

Lists the nightmare fields: AI with Q* at OpenAI, synthetic biology, grey-goo nanotechnology, quantum computers, and dystopian global systems, warning blockchain could be evil if misused.

Shows the 2018 DEFUSE proposal to DARPA from the Wuhan Institute, UNC, Duke, USGS, PARC, and EcoHealth to catalog bat coronaviruses and build vaccines using humanized mice.

The March 2018 document is a blueprint for building a COVID virus that DARPA rejected as too risky, and that Dr Shi ran the lab it likely leaked from.

Responds to Elizabeth Warren mocking his credentials, recounting his Front Range Community College associate degree, transfer to Metro State, and a CU Boulder dual graduate program.

On Lace, says they acquired Nami and want it merged in as a beginner Nami mode, for now running parallel tracks that will intersect.

Legends of Valor has dialogue and a plot but he wants a AAA game taking 3 to 6 years, done in-house, while the game studio Reflect ships Girl Fight in March, led by Les Borsai, Eric, and Josh.

On who built Bitcoin, says a solo coder worked from 2007 to 2008 and launched early 2009, with stylometry on the C++ suggesting one author, most likely Adam Back who created proof of work.

Terminators are 3 to 5 years away since the Pentagon wants autonomous drones making independent kill decisions, and that his ranch produces about 120 bison a year.

Predicts the singularity in 5 to 10 years, explaining LLM training on Transformer networks over H100 clusters, with parameter counts from 60 million to multi-trillion and rising inference cost.

Neuromorphic computing from Rain AI uses memristors a thousand times more energy-efficient for inference, and that synthetic data simulates rare edge cases like a Tesla seeing a flaming truck rollover.

RLHF is the most time-consuming alignment step, and that Anthropic's AI Constitution uses RLAIF to align Claude, replacing human feedback with AI feedback.

Cognitive agents with long-term memory and dynamic token space are the sparks of AGI, all near-horizon, letting one person run a self-improving 10,000-person AI organization.

Sam Altman was too busy becoming OpenAI's CEO again to accept his invitation, and wonders what Ilya Sutskever knows, tied to the excitement around Q*.

Calls synthetic meat the biggest waste of money he has seen, like vertical farming that only grows cabbage, and mentions using Hostage Tape to mouth-tape when he sleeps.

The Mandela effect, Berenstain versus Berenstein, where ruminating makes a memory seem different from what it was, which he has experienced significantly.

On the ethics of meat, asks why a lion eating a gazelle is just but human meat-eating is not, since something must die for humans to live.

His sustainable free-range bison on 11,000 acres with guided hunts, low-stress and zero-waste, contrasting it with terrible chicken farming.

Humans evolved as omnivores and it is very hard to get all nutrients from plants alone, so people should not claim humans do not need meat.

ASU claimed his recovered microspherules are coal ash but the graphs are clearly different, to be cleaned up in the spring paper with real samples.

Stresses a good microbiome to digest food, and argues refined sugar rather than red meat causes cancer, citing balanced 19th-century diets.

2024 is a dry no-drinking year, that high-fructose corn syrup is the worst of the worst, and Mexican Coca-Cola with cane sugar is much better.

Calls fasting done responsibly the single best thing for your health, and notes saturated fat only causes heart disease when combined with excess carbs.

On testosterone replacement therapy, advises losing body fat and lifting weights first, since excess fat converts testosterone, before considering injections.

On a Hosk.said question, shows a strange book resembling the Codex Seraphinianus, and says the big difference between Cardano and Polkadot partner chains is Minotaur.

He uses every operating system with Qubes for segregation and Ubuntu for work, and would love an objective media platform connecting dots like US proxy-war spending.

He did not staff the independent Cardano Foundation or Emurgo, and that input endorsers would significantly change the monetary policy and emission schedule.

Offers to interview presidential candidate Vivek Ramaswamy if listeners reach his campaign, and says he would love to return to the Lex Fridman podcast.